| Shodensha | Japon | 3 |
| Shoemaker and Hoard | | 1 |
| Shogakukan | Japon | 269 |
| Short Books | France | 7 |
| ShortBox | | 2 |
| shortÉdition | France | 3 |
| Shoubunkan | Japon | 2 |
| ShuCream | Japon | 2 |
| Shueisha | Japon | 486 |
| Shufu to Seikatsu Sha | Japon | 1 |
| Sidestone Press | Pays-Bas | 1 |
| Sidgwick & Jackson | | 2 |
| Sidh Press | | 94 |
| Siena | France | 1 |
| Sigest | France | 2 |
| Sigilo | Argentine | 2 |
| Siglo XXI | | 4 |
| Signatura | France | 4 |
| Signe de piste | France | 6 |
| Signes et Balises | | 3 |
| Signet | Etats-Unis | 166 |
| Silberburg Verlag | Allemagne | 1 |
| Silenium Créations | France | 3 |
| Silk Thread Publishing | Canada | 5 |
| Sillage | France | 106 |
| Sillex | | 9 |
| Silly Cat | France | 2 |
| Siloë | France | 16 |
| Silvana | | 13 |
| Silver Griffon Associates | | 15 |
| Silver Press | | 5 |
| Silver Wing Press | Etats-Unis | 34 |
| SilverWood Books | Angleterre | 2 |
| Simon & Schuster | Etats-Unis | 1439 |
| Simon Pulse | Etats-Unis | 293 |
| Simon Spotlight Entertainment | France | 4 |
| Simple IT | France | 2 |
| SimpleDad | France | 1 |
| Sinauer Associates | France | 1 |
| Sindbad | France | 16 |
| Sindbadboy | France | 8 |
| Sine Qua Non | Pologne | 2 |
| Singing dragon | Angleterre | 5 |
| Singulières | | 4 |
| Sinner Publishing | | 14 |
| Sinnos | Italie | 1 |
| Sinope | | 1 |
| Sioni | France | 21 |
| SIPE | France | 3 |
| SIREC | | 1 |
| Siren Publishing | Etats-Unis | 28 |
| Siri Scientific | Angleterre | 0 |
| Sirius | France | 11 |
| Siruela | | 9 |
| Sister and Brother | | 1 |
| Sitelle | France | 1 |
| Six Brumes | France | 3 |
| Six citrons acides | France | 3 |
| Sixto | France | 8 |
| Sixtrid | France | 122 |
| Ska | | 66 |
| Skipstone | Etats-Unis | 1 |
| Skira | France | 18 |
| Skits | France | 1 |
| Skol Vreizh | France | 12 |
| Sky Comm | France | 3 |
| Sky Pony Press | Etats-Unis | 13 |
| Skybound | Etats-Unis | 14 |
| Skyhorse | Etats-Unis | 37 |
| Skylark Publishing | | 2 |
| Skyscape | Etats-Unis | 35 |
| Slalom | France | 219 |
| Slatkine | Suisse | 93 |
| Slatkine & Cie | France | 115 |
| Sleeping Bear Press | Etats-Unis | 5 |
| Slen | France | 1 |
| SLG | France | 4 |
| SM | Espagne | 21 |
| Small Beer Press | Etats-Unis | 17 |
| Smart Cat | | 3 |
| Smart Pop | France | 6 |
| Smartpop Books / Benbella Books | France | 2 |
| Smartypants Romance | | 4 |
| Smashwords | France | 197 |
| SMBC | | 1 |
| Smith & Kraus | Etats-Unis | 5 |
| Smith Street Books | Australie | 3 |
| Smithsonian Books | | 4 |
| Snag | | 54 |
| SNCF | France | 1 |
| Snoeck | | 17 |
| Snorgleux Comics | France | 21 |
| Snowbooks | Angleterre | 7 |
| So Lonely | | 6 |
| So romance | | 182 |
| SOBEPS | Belgique | 0 |
| Sobisha | Japon | 1 |
| Sochepress | | 2 |
| Sociales | | 47 |
| Socialter | France | 2 |
