Star Trek: The Brave and the Bold, book 1
Keith R. A. DeCandido2002

The Malkus Artifacts: four deadly machines, wielded as weapons of absolute power by an interstellar tyrant thousands of years ago and scattered across the Alpha Quadrant when he was overthrown. After their existence was discovered in 2151 by Captain Jonathan Archer of the Starship Enterprise, all Starfleet vessels were warned to keep an eye out for these most dangerous devices...

One hundred years later, Captain James T. Kirk of the U.S.S. Enterprise and Commodore Matt Decker of the U.S.S. Constellation come across the first artifact on the colony world of Alpha Proxima II – a world ravaged by a mysterious plague. As the crews of the two mighty vessels work to find a cure and locate the artifact, two brave captains must bring order to Proxima before it's too late!

One hundred years after that, Commander Benjamin Sisko of Space station Deep Space 9 enlists the aid of Captain Declan Keogh of the U.S.S. Odyssey to help construct a farming colony on Bajor's second moon – but the colony is placed in jeopardy when the Bajoran terrorist Orta discovers the second artifact and threatens destruction on a massive scale!